Post-Translational Modification-specific Antibodies

Post-Translational Modifications (PTMs) are highly dynamic and often reversible processes where protein functional properties are altered by addition of a chemical group or another protein to its amino acid residues. Most of these PTMs preferentially take place on tubulin subunits already incorporated into microtubules. It has been shown that microtubule PTMs deregulation have impact on neuronal development and diseases.