Viral innate sensor

Recently, the lab of Prof. Siddharth Balachandran shows in CELL that the protein ZBP1 detects a certain form of viral RNA (Z-form) in the nucleus triggering the kinase MLKL1, consequently leading to nuclear enveloppe disruption, DNA leaking and necroptosis.
They used anti-ZBP1, mAb (Zippy-1) (Prod. No. AG-20B-0010) from AdipoGen Life Sciences in their studies, confirming the specificity of Zippy-1 in mouse (ZBP1 KO mice) and human cells. Reference.

COVID-19 Reagents

The ongoing pandemic of the newly identified coronavirus COVID-19 has been declared a public health emergency of international concern by the WHO. Several of our suppliers offer products to assist the research related to this virus.

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Webinar: The Human Protein Atlas

Join speaker Cecilia Lindskog, PhD, Director of the Human Protein Tissue Atlas for the webinar on integration of transcriptomics and antibody-based proteomics for cell type-specific localization of SARS-CoV-2 related proteins.

When: Thursday, June 11, 2020 from 4 PM to 5 PM (CEST)

Register now, the seats are limited.