Bio-Connect

anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin)

Research Use Only
AG-20B-0044B
AdipoGen Life Sciences
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse
TargetCasp1
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    anti-Caspase-1 (p10) (mouse), mAb (Casper-2) (Biotin)
  • Delivery Days Customer
    10
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    Casper-2
  • Concentration
    1 mg/ml
  • Conjugate
    Biotin
  • Estimated Purity
    >95%
  • Gene ID12362
  • Target name
    Casp1
  • Target description
    caspase 1
  • Target synonyms
    Casp; CASP-1; caspase-1; IC; ICE; Il1; IL-1 beta-converting enzyme; IL-1B converting enzyme; Il1bc; IL-1BC; interleukin-1 beta convertase; interleukin-1 beta-converting enzyme; p45
  • Host
    Mouse
  • Isotype
    IgG2a
  • Scientific Description
    Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals. - Monoclonal Antibody. Recognizes endogenous full-length and activated (p10 fragment) mouse caspase-1. Isotype: Mouse IgG2a. Clone: Casper-2. Applications: WB. Liquid. In PBS containing 0.02% sodium azide. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic flagellin, murine NLRP1b responds to anthrax lethal toxin, AIM2 responds to cytosolic DNA and NLRP3 responds to a variety of agonists including crystals.
  • Reactivity
    Mouse
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352203